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mouse neuroblastoma cell line n2a  (ATCC)


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    ATCC mouse neuroblastoma cell line n2a
    Mouse Neuroblastoma Cell Line N2a, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 4221 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/n2a+mouse+neuroblastoma+cell+line/Neuro-2a/pm42120407-428-0-5
    Average 99 stars, based on 4221 article reviews
    mouse neuroblastoma cell line n2a - by Bioz Stars, 2026-09
    99/100 stars

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    other:

    Article Title: Linear Polyethyleneimine-Coated Gold Nanoparticles as a Platform for Central Nervous System Targeting.
    Article Snippet: The N2a mouse neuroblastoma cell line (ATCC No. CCL-131), the BV-2 murine microglial cell line [30], the OLN93 rat oligodendroglial cell line [31], and the NIH-3T3 mouse fibroblast cell line (ATCC No. CRL-1658) were kindly provided by Dr. Juana Pasquini’s laboratory (Universidad de Buenos Aires, Buenos Aires, Argentina).

    Article Title: Linear Polyethyleneimine-Coated Gold Nanoparticles as a Platform for Central Nervous System Targeting
    Article Snippet: The N2a mouse neuroblastoma cell line (ATCC No. CCL-131), the BV-2 murine microglial cell line [ ], the OLN93 rat oligodendroglial cell line [ ], and the NIH-3T3 mouse fibroblast cell line (ATCC No. CRL-1658) were kindly provided by Dr. Juana Pasquini’s laboratory (Universidad de Buenos Aires, Buenos Aires, Argentina).

    Modification:

    Article Title: Computer-aided discovery of novel AMPK activators through virtual screening and SAR-driven synthesis.
    Article Snippet: AMPK is a promising target for various chronic illnesses such as diabetes and Alzheimer’s disease (AD).. We sought to develop a novel small molecule that directly activates AMPK, with the potential to fundamentally modulate the pathogenic mechanisms of the metabolic disorders.. To identify a potent novel pharmacophore in an unbiased way, we performed structure-based virtual screening on a commercially available chemical library, and evaluated the actual AMPK activity of 118 compounds selected from 100,000 compounds based on docking scores.



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    mouse neuroblastoma cell line n2a  (ATCC)
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    neuro 2a n2a mouse neuroblastoma cell lines  (ATCC)
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    Abcam ab64186 recognizes NRN1 protein in mouse <t>neuroblastoma</t> cells. (A) Representative Western blot of human embryonic kidney (HEK) <t>293T,</t> <t>Neuro‐2a</t> <t>(N2a)</t> mouse neuroblastoma, and SH‐SY5Y human neuroblastoma cell lysates (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186 and GAPDH monoclonal antibody. (B) N2a cells were transfected with NRN1 or Scramble (non‐targeting) siRNA smart pools and harvested after 96 h. Western blot analyses with NRN1 polyclonal antibody Abcam ab64186 revealed reduced intensity of the ∼34 kDa band in NRN1‐depleted cells, compared to Scramble control. 10 µg of protein was loaded per lane, and GAPDH was probed as a loading control. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; NRN1, Neuritin‐1; siRNA, small interfering RNA;
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    n2a mouse neuroblastoma cell line  (ATCC)
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    Abcam ab64186 recognizes NRN1 protein in mouse <t>neuroblastoma</t> cells. (A) Representative Western blot of human embryonic kidney (HEK) <t>293T,</t> <t>Neuro‐2a</t> <t>(N2a)</t> mouse neuroblastoma, and SH‐SY5Y human neuroblastoma cell lysates (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186 and GAPDH monoclonal antibody. (B) N2a cells were transfected with NRN1 or Scramble (non‐targeting) siRNA smart pools and harvested after 96 h. Western blot analyses with NRN1 polyclonal antibody Abcam ab64186 revealed reduced intensity of the ∼34 kDa band in NRN1‐depleted cells, compared to Scramble control. 10 µg of protein was loaded per lane, and GAPDH was probed as a loading control. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; NRN1, Neuritin‐1; siRNA, small interfering RNA;
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    mouse n2a neuroblastoma ccl 131 cell lines  (ATCC)
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    ATCC mouse n2a neuroblastoma ccl 131 cell lines
    Abcam ab64186 recognizes NRN1 protein in mouse <t>neuroblastoma</t> cells. (A) Representative Western blot of human embryonic kidney (HEK) <t>293T,</t> <t>Neuro‐2a</t> <t>(N2a)</t> mouse neuroblastoma, and SH‐SY5Y human neuroblastoma cell lysates (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186 and GAPDH monoclonal antibody. (B) N2a cells were transfected with NRN1 or Scramble (non‐targeting) siRNA smart pools and harvested after 96 h. Western blot analyses with NRN1 polyclonal antibody Abcam ab64186 revealed reduced intensity of the ∼34 kDa band in NRN1‐depleted cells, compared to Scramble control. 10 µg of protein was loaded per lane, and GAPDH was probed as a loading control. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; NRN1, Neuritin‐1; siRNA, small interfering RNA;
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    Abcam ab64186 recognizes NRN1 protein in mouse neuroblastoma cells. (A) Representative Western blot of human embryonic kidney (HEK) 293T, Neuro‐2a (N2a) mouse neuroblastoma, and SH‐SY5Y human neuroblastoma cell lysates (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186 and GAPDH monoclonal antibody. (B) N2a cells were transfected with NRN1 or Scramble (non‐targeting) siRNA smart pools and harvested after 96 h. Western blot analyses with NRN1 polyclonal antibody Abcam ab64186 revealed reduced intensity of the ∼34 kDa band in NRN1‐depleted cells, compared to Scramble control. 10 µg of protein was loaded per lane, and GAPDH was probed as a loading control. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; NRN1, Neuritin‐1; siRNA, small interfering RNA;

    Journal: Alzheimer's & Dementia

    Article Title: NRN1 as a therapeutic target for Alzheimer's disease

    doi: 10.1002/alz.71149

    Figure Lengend Snippet: Abcam ab64186 recognizes NRN1 protein in mouse neuroblastoma cells. (A) Representative Western blot of human embryonic kidney (HEK) 293T, Neuro‐2a (N2a) mouse neuroblastoma, and SH‐SY5Y human neuroblastoma cell lysates (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186 and GAPDH monoclonal antibody. (B) N2a cells were transfected with NRN1 or Scramble (non‐targeting) siRNA smart pools and harvested after 96 h. Western blot analyses with NRN1 polyclonal antibody Abcam ab64186 revealed reduced intensity of the ∼34 kDa band in NRN1‐depleted cells, compared to Scramble control. 10 µg of protein was loaded per lane, and GAPDH was probed as a loading control. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; NRN1, Neuritin‐1; siRNA, small interfering RNA;

    Article Snippet: Neuro‐2a (N2a) mouse neuroblastoma cell lines (Catalog No.: CCL‐131, ATCC) were maintained in MEM (Catalog No.: 11095‐080, Thermo Fisher Scientific) with 10% FBS and 1% penicillin‐streptomycin.

    Techniques: Western Blot, Transfection, Control, Small Interfering RNA